Chemotherapy for soft tissue sarcoma
نویسندگان
چکیده
منابع مشابه
Histology-driven chemotherapy of soft-tissue sarcoma.
Soft-tissue sarcomas are rare diseases with >50 subtypes. Surgery is the most important treatment in localized disease, sometimes combined with radiotherapy. Chemotherapy is used as palliation in advanced disease, sometimes also with a potential to decrease tumour size and eradicate micro-metastases, making meaningful surgery possible. The role of chemotherapy as adjuvant treatment in localized...
متن کاملMetastatic soft tissue sarcoma chemotherapy: an opportunity for personalized medicine.
BACKGROUND Soft tissue sarcoma (STS) includes biologically and histologically diverse mesenchymal tumors that are relatively chemotherapy-resistant compared with other sarcoma subtypes. METHODS The authors discuss the clinical challenges frequently encountered by medical oncologists and review the literature for predictive strategies to systematically approach chemotherapy decision making. ...
متن کاملAdjuvant Chemotherapy of Soft Tissue Sarcoma—Current Status
It is acknowledged that, although improvements can be made in local control, e.g. by the use of adjuvant radiotherapy, the major challenge in the management of adult soft tissue sarcomas is the treatment of distant metastatic disease.We lack very effective drugs capable of providing long-term disease control once this event has occurred. Palliation is possible with doxorubicin, ifosfamide or co...
متن کاملSoft tissue sarcoma.
Soft tissue sarcomas are rare tumours of the connective tissue. The knowledge of this rare entity is necessary for an accurate diagnosis. The incidence in Europe is about 3,6/100 000 per year. The first line treatment consists of a wide resection of the tumour, possibly combined with an adjuvant radiation therapy. A chemotherapy can be indicated and has to be evaluated for each case individuall...
متن کاملSoft-tissue sarcoma.
Soft-tissue sarcomas are rare malignancies of mesodermal origin. Common sites of involvement include the extremities, trunk, retroperitoneum, and the head and neck. Soft-tissue sarcomas of the extremities and pelvis are the most relevant to the orthopaedic surgeon. The patient with extremity soft-tissue sarcoma typically presents with a painless, enlarging mass. Advanced imaging techniques and ...
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ژورنال
عنوان ژورنال: Cancer
سال: 2016
ISSN: 0008-543X
DOI: 10.1002/cncr.30191